valium half life elderly

There is a high prevalence of long-term benzodiazepine use among elderly persons persons aged 65 years or older who account for 125 percent of the general. Absorption of diazepam was faster than oxazepam and onset of clinical effects were more pro.


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Oxazepam and diazepam were compared in healthy elderly volunteers.

. More recent studies have indicated that excessive benzodiazepine dosage may be a more salient factor than drug half-life. Furthermore alterations in phar. Once diazepam breaks down into these substances they can be eliminated from the.

In full term infants elimination half-lives around 30 hours have been reported with. In full term infants elimination half-lives around 30 hours have been reported with. In children 3 - 8 years old the mean half-life of diazepam has been reported to be 18 hours.

To determine how long the chemical diazepam within Valium stays in your system after stopping it is necessary to review its elimination half-life. In children 3 - 8 years old the mean half-life of diazepam has been reported to be 18 hours. Longer half-lives such as chlor-diazepoxide diazepam and flu-razepam are more likely to accumu-late in the body and cause prolonged sedation 10.

Oxazepam has a half-life of 4-15 hours while temazepam has a half-life of 8-22 hours. Diazepam accumulates upon multiple dosing and the terminal elimination half-life is slightly prolonged. 48 According to Beers 1997 criteria for determining.


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